Czech J. Anim. Sci., 2015, 60(7):311-318 | DOI: 10.17221/8277-CJAS

Mitochondrial diversity in autochthonous cattle breeds from the Balkan PeninsulaOriginal Paper

P. Hristov1, D. Teofanova1, B. Neov1, B. Shivachev2, G. Radoslavov1
1 Department of Animal Diversity and Resources, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, Sofia, Bulgaria
2 Department of Structural Crystallography and Materials Science, Laboratory of X-ray Diffraction Analysis, Institute of Mineralogy and Crystallography, Bulgarian Academy of Sciences, Sofia, Bulgaria

The Bulgarian Grey Cattle (BGC) and Shorthorn Rhodopean Cattle (SRC) are indigenous breeds from the Balkan Peninsula region. The Balkans, as part of Southeast Europe, is a crucial civilization crossroad of cultures, people, and livestock. This region is considered the civilization "cradle" of prehistoric times (around 6500 BC). The aim of the present study is to reveal the genetic profile and population structure of BGC and SRC according to displacement loop control region. The results showed that these ancient cattle breeds belong to the common T1, T2, and T3 haplogroups. Within the BGC population the T3a sub-haplogroup was predominant (about 80% - 31/39) with haplotypes BGC-4.1 (33% - 13/39) and BGC-4.2 (about 40% - 16/39). Mitochondrial DNA analysis of SRC population showed a heterogeneous structure consisting of five basic haplo- and sub-haplogroups, all based on twelve haplotypes with equal frequencies. Based on 173G polymorphic site newly named sub-haplogroup T3c was proposed. A detailed comparative analysis with other Balkan cattle populations was performed. Data showed multiple haplotype mtDNA profile with no phylogenetic relationships within.

Keywords: autochthonous cattle; domestication; D-loop region; genetic diversity

Published: July 31, 2015  Show citation

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Hristov P, Teofanova D, Neov B, Shivachev B, Radoslavov G. Mitochondrial diversity in autochthonous cattle breeds from the Balkan Peninsula. Czech J. Anim. Sci. 2015;60(7):311-318. doi: 10.17221/8277-CJAS.
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    References

    1. Achilli A., Olivieri A., Pellecchia M., Uboldi C., Colli L., AlZahery N., Accetturo M., Pala M., Kashani B.H., Perego U.A., Battaglia V., Fornarino S., Kalamati J., Houshmand M., Negrini R., Semino O., Richards M., Macaulay V., Ferretti L., Bandelt H.J., Ajmone-Marsan P., Torroni A. (2008): Mitochondrial genomes of extinct aurochs survive in domestic cattle. Current Biology, 18, R157-R158. Go to original source... Go to PubMed...
    2. Achilli A., Bonfiglio S., Olivieri A., Malusa A., Pala M., Hooshiar Kashani B., Perego U.A., Ajmone-Marsan P., Liotta L., Semino O., Bandelt H.J., Ferretti L., Torroni A. (2009): The multifaceted origin of taurine cattle reflected by the mitochondrial genome. PLoS One, 4: e5753. Go to original source... Go to PubMed...
    3. Ajmone-Marsan P., Garcia J.F., Lenstra J.A. (2010): On the origin of cattle: how aurochs became cattle and colonized the world. Evolutionary Anthropology, 19, 148-157. Go to original source...
    4. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. (1990): Basic local alignment search tool. Journal of Molecular Biology, 215, 403-410. Go to original source... Go to PubMed...
    5. Anderson S., de Bruijn M.H., Coulson A.R., Eperon I.C., Sanger F., Young I.G. (1982): Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome. Journal of Molecular Biology, 156, 683-717. Go to original source... Go to PubMed...
    6. Beja-Pereira A., Caramellic D., Lalueza-Foxe C., Vernesif C., Ferranda N., Casolih A., Goyachei F., Royoi L.J., Contid S., Lari M., Martini A., Ouragh L., Magid A., Atash A., Zsolna A., Boscato P., Triantaphylidis C., Ploumi K., Sineo L., Mallegni F., Taberlet P., Erhardt G., Sampietro L., Bertranpetit J., Barbujani G., Luikart G., Bertorellec G. (2006): The origin of European cattle: evidence from modern and ancient DNA. Proceedings of the National Academy of Sciences of the United States of America, 103, 8113-8118. Go to original source... Go to PubMed...
    7. Bonfiglio S., Achilli A., Olivieri A., Negrini R., Colli L., Liotta L., Ajmone-Marsan P., Torroni A., Ferretti L. (2010): The enigmatic origin of bovine mtDNA haplogroup R: Sporadic interbreeding or an independent event of Bos primigenius domestication in Italy? PLoS One, 5: e15760. Go to original source... Go to PubMed...
    8. Bradley D.G., MacHugh D.E., Cunningham P., Loftus R.T. (1996): Mitochondrial diversity and the origins of African and European cattle. Proceedings of the National Academy of Sciences of the United States of America, 93, 5131-5135. Go to original source... Go to PubMed...
    9. Bradley D.G., Loftus R.T., Cunningham P., MacHugh D.E. (1998): Genetics and domestic cattle origins. Evolutionary Anthropology, 6, 79-86. Go to original source...
    10. Chen S., Lin B.-Z., Baig M., Mitra B., Lopes R.J., Santos A.M., Magee D.A., Azevedo M., Tarroso P., Sasazaki S., Ostrowski S., Mahgoub O., Chaudhuri T.K., Ya-Ping Z., Costa V., Royo L.J., Goyache F., Luikart G., Boivin N., Fuller D.Q., Mannen H., Bradley D.G., Beja-Pereira A. (2010): Zebu cattle are an exclusive legacy of the South Asia Neolithic. Molecular Biology and Evolution, 27, 1-6. Go to original source... Go to PubMed...
    11. Cortes O., Tupac-Yupanqui I., Dunner S., Garcia-Atance M.A., Garcia D., Fernandez J., Canon J. (2008): Ancestral matrilineages and mitochondrial DNA diversity of the Lidia cattle breed. Animal Genetics, 39, 649-654. Go to original source...
    12. Ivankovic A., Ramljak J., Dovc P. (2012): Mitochondrial genetic variation in two Podolian cattle breeds in Croatia. In: Book of Abctracts of the 63rd Annual Meeting of the European Federation of Animal Science. Wageningen Academic Publishers, Wageningen, the Netherlands, 12.
    13. Kantanen J., Edwards C.J., Bradley D.G., Viinalass H., Thessler S., Ivanova Z., Kiselyova T., Cinkulov M., Popov R., Stojanovic S., Ammosov I., Vilkki J. (2009): Maternal and paternal genealogy of Eurasian taurine cattle Bos taurus. Heredity, 103, 404-415. Go to original source... Go to PubMed...
    14. Kimura M. (1980): A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences. Journal of Molecular Evolution, 16, 111-120. Go to original source... Go to PubMed...
    15. Lai S.J., Liu Y.P., Liu Y.X., Li X.W., Yao Y.G. (2006): Genetic diversity and origin of Chinese cattle revealed by mtDNA D-loop sequence variation. Molecular Phylogenetics and Evolution, 38, 146-154. Go to original source... Go to PubMed...
    16. Loftus R.T., MacHugh D.E., Bradley D.G., Sharp P.M., Cunningham P. (1994): Evidence for two independent domestications of cattle. Proceedings of the National Academy of Sciences of the United States of America, 91, 2757-2761. Go to original source... Go to PubMed...
    17. Ludwig A., Alderson L., Fandrey E., Lieckfeldt D., Soederlund T.K., Froelich K. (2013): Tracing the genetic roots of the indigenous White Park Cattle. Animal Genetics, 44, 383-386. Go to original source... Go to PubMed...
    18. Mannen H., Kohno M., Nagata Y., Tsuji S., Bradley D.G., Yeo J.S., Nyamsamba D., Zagdsuren Y., Yokohama M., Nomura K., Amano T. (2004): Independent mitochondrial origin and historical genetic differentiation in North Eastern Asian cattle. Molecular Phylogenetics and Evolution, 32, 539-544. Go to original source... Go to PubMed...
    19. Maretto F., Ramljak J., Sbarra F., Penasa M., Mantovani R., Ivankovic A., Bittante G. (2012): Genetic relationships among Italian and Croatian Podolian cattle breeds assessed by microsatellite markers. Livestock Science, 150, 256-264. Go to original source...
    20. Mason I.L. (1996): A World Dictionary of Livestock Breeds, Types and Varieties. CAB International, Wallingford, UK.
    21. Meadow R.H. (1993): Animal domestication in the Middle East: a revised view from the eastern margin. In Possehl G. (ed.): Harappan Civilization. Oxford University Press and India Book House, New Delhi, India, 295-320.
    22. Mirol P.M., Giovambattista G., Liron J.P., Dulout F.N. (2003): African and European mitochondrial haplotypes in South American Creole cattle. Heredity, 91, 248-254. Go to original source... Go to PubMed...
    23. Orton D. (2012): Herding, settlement and chronology in the Balkan Neolithic. European Journal of Archaeology, 15, 5-40. Go to original source...
    24. Russell N. (1998): Cattle as wealth in Neolithic Europe: where's the beef? In: Bailey D. (ed.): The Archaeology of Value: Essays on Prestige and the Process of Valuation. BARIS Press, Oxford, UK, 42-54.
    25. Soysal M.I., Kok S. (2008): The last survivors of Grey cattle resisting extinction. A case study of characteristics and sustainability of traditional systems of native Grey cattle breeds. In : Olaizola A., Boutonnet J.P., Bernues A. (eds): Mediterranean Livestock Production: Uncertainties and Opportunities. Options Méditerranéennes: Series A. Mediterranean Seminars, 78, 55-63.
    26. Tamura K., Peterson D., Peterson N., Stecher G., Nei M., Kumar S. (2011): MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Molecular Biology and Evolution, 28, 2731-2739. Go to original source... Go to PubMed...
    27. Troy C.S., MacHugh D.E., Bailey J.F., Magee D.A., Loftus R.T., Cunningham P., Chamberlain A.T., Sykes B.C., Bradley D.G. (2001): Genetic evidence for Near-Eastern origins of European cattle. Nature, 410, 1088-1099. Go to original source... Go to PubMed...

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