Czech J. Anim. Sci., 2010, 55(5):195-199 | DOI: 10.17221/101/2009-CJAS

Associations between the bovine PPARGC1A gene and milk production traits

I. Kowalewska-£uczak, H. Kulig, M. Kmieĉ
Department of Genetics and Animal Breeding, West Pomeranian University of Technology, Szczecin, Poland

The aim of this study was to investigate associations between PPARGC1A genotypes and haplotypes and milk production traits. The study included 181 Jersey cows. The genotypes were identified by the PCR-RFLP method. The frequencies of the most common alleles were as follows: T - 0.63 (c.1892T>C) and A - 0.88 (c.3359A>C). The frequency of the most common haplotype was TC/AA - 0.558. The results showed that there were no statistically significant associations between the individual genotypes of both SNPs and milk traits; however, individuals with the CC/AC haplotype produced significantly (P ≤ 0.05; P ≤ 0.001) less milk and had a significantly (P ≤ 0.001) higher protein content in milk.

Keywords: cattle; PPARGC1A gene; PCR-RLP; milk traits

Published: May 31, 2010  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Kowalewska-£uczak I, Kulig H, Kmieĉ M. Associations between the bovine PPARGC1A gene and milk production traits. Czech J. Anim. Sci. 2010;55(5):195-199. doi: 10.17221/101/2009-CJAS.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Hradecká E., Èítek J., Panicke L., Ĝehout V., Hanusowá L. (2008): The relation of GH1, GHR and DGAT1 polymorphisms with estimated breeding values for milk production traits of German Holstein sires. Czech Journal of Animal Science, 53, 238-245. Go to original source...
    2. Khatib H., Zaitoun I., Wiebelhaus-Finger J., Chang Y.M., Rosa G.J.M. (2007): The association of bovine PPARGC1A and OPN genes with milk composition in two independent Holstein cattle populations. Journal of Dairy Science, 90, 2966-2970. Go to original source... Go to PubMed...
    3. Khatkar M.S., Thomson P.C., Tammen I., Raadsma H.W. (2004): Quantitative trait loci mapping in dairy cattle: review and meta-analysis. Genetics Selection Evolution, 36, 163-190. Go to original source... Go to PubMed...
    4. Liang H., Ward W.F. (2006): PGC-1α: a key regulator of energy metabolism. Advances in Physiology Education, 30, 145-151. Go to original source... Go to PubMed...
    5. Pan C.Y., Lan X.Y., Chen H., Yanng D.Y., Hua L.S., Yang X.B., Lei C.Z., Guo Y.K., Zhang C.L., Kang X.T., Wang I.Q. (2008): A DdeI PCR-RFLP detecting a novel missense mutation of the POU1F1 gene showed no effects on growth traits in cattle. Czech Journal of Animal Science, 53, 523-527. Go to original source...
    6. Puigserver P., Spiegelman B.M. (2003): Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1&alpha): transcriptional coactivator and metabolic regulator. Endocrine Reviews, 24, 78-90. Go to original source... Go to PubMed...
    7. Statsoft (2006): Data Analysis Software System, Statistica, version 7.1. StatSoft, Poland.
    8. Weikard R., Kühn Ch., Goldammer T., Freyer G., Schwerin M. (2005): The bovine PPARGC1A gene: molecular characterization and association of an SNP with variation of milk fat synthesis. Physiological Genomics, 21, 1-13. Go to original source... Go to PubMed...

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content