Czech J. Anim. Sci., 2009, 54(10):443-447 | DOI: 10.17221/1673-CJAS

The visfatin (NAMPT; PBEF1) gene polymorphisms and associations with meat performance traits in three pig breeds kept in the Czech Republic

J. Zrůstová1, A. Knoll1,2, T. Urban1, S. Čepica2
1 Department of Animal Morphology, Physiology and Genetics, Mendel University of Agriculture and Forestry in Brno, Brno, Czech Republic
2 Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, Liběchov, Czech Republic

Visfatin encoded by the NAMPT gene (nicotinamide phosphoribosyltransferase, formerly also known as PBEF - pre-B cell colony-enhancing factor) is suggested to play a role in lipid metabolism and pathophysiology of diabetes mellitus type 2. A new microsatellite SCZ004 was detected within intron 9 of the NAMPT gene. In Czech Large White (n = 95) frequencies of alleles 282, 286, 287, 299, and 304 were 0.02, 0.39, 0.07, 0.04, and 0.48, respectively. Allele 286 was predominant also in Landrace (n = 11) and Black Pied Prestice (n = 11) breeds. Association analysis was carried out between previously reported SNP AM999341:g.669T>C in intron 9 of the NAMPT gene and backfat thickness, average daily gain and lean meat content in Czech Large White (n = 215), Black Pied Prestice (n = 96) and Landrace (n = 105). The CC genotype was associated with higher backfat thickness (

Keywords: visfatin; NAMPT; PBEF; SNP; microsatellite; pig; association analysis

Published: October 31, 2009  Show citation

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Zrůstová J, Knoll A, Urban T, Čepica S. The visfatin (NAMPT; PBEF1) gene polymorphisms and associations with meat performance traits in three pig breeds kept in the Czech Republic. Czech J. Anim. Sci. 2009;54(10):443-447. doi: 10.17221/1673-CJAS.
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