Czech J. Anim. Sci., 2023, 68(12):508-515 | DOI: 10.17221/133/2023-CJAS

Effect of catalase on the growth performance, antioxidation, and microbial metabolism of weaned rabbitsOriginal Paper

Ning Liu ORCID...1, Yien Lin ORCID...1, Shuaibao Wang ORCID...2, Jianping Wang1
1 Department of Animal Science, Henan University of Science and Technology, Luoyang, PR China
2 Center of Animal Disease Control, Municipal Bureau of Agriculture and Rural Affair, Sanmenxia, PR China

The present study aimed to investigate the effect of catalase (CAT) on the growth performance, antioxidation, and microbial metabolism of weaned rabbits. Dietary treatments consisted of control and CAT supplementation at 100 (T1), 150 (T2), and 200 IU/kg of diet (T3). A total of 240 weaned rabbits were randomly assigned to 4 groups with 6 replicates of 10 rabbits each. The feeding trial lasted for 28 days. Results showed that T2 and T3 increased (P < 0.05) body weight gain and gain/feed ratio, and decreased (P < 0.05) diarrhoea rate, compared to the control. Also, serum antioxidative parameters and oxidative stress products were beneficially regulated (P < 0.05) by the dietary CAT administration. Faecal microbiota including Bacteroidetes, Prevotella, and Bifidobacterium in T2 or T3 was increased (P < 0.05). Dietary CAT with changed microbiota further influenced the metabolites from carbohydrates and proteins, evidenced by increased lactic acid, acetate, branched-chain fatty acids, and short-chain fatty acids, and decreased valerate, isovalerate, methylamine, tryptamine, putrescine, cadaverine, spermidine, and total amines. It is concluded that CAT can be used to improve growth performance by beneficially regulating the antioxidation, microbiota, and metabolites in weaned rabbits.

Keywords: amine; gut microbe; short-chain fatty acid; oxidant injury product

Received: October 10, 2023; Accepted: December 7, 2023; Published: December 20, 2023  Show citation

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Liu N, Lin Y, Wang S, Wang J. Effect of catalase on the growth performance, antioxidation, and microbial metabolism of weaned rabbits. Czech J. Anim. Sci. 2023;68(12):508-515. doi: 10.17221/133/2023-CJAS.
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    References

    1. Alomar M, Alzoabi M, Zarkawi M. Kinetics of hydrogen peroxide generated from live and dead ram spermatozoa and the effects of catalase and oxidase substrates addition. Czech J Anim Sci. 2016 Jan 31;61(1):1-7. Go to original source...
    2. AOAC - Association of Official Analytical Chemists. Official Methods of Analysis. 18th ed. Artington: Association of Official Analytical Chemists; 2007.
    3. Baker A, Lin CC, Lett C, Karpinska B, Wright MH, Foyer CH. Catalase: A critical node in the regulation of cell fate. Free Radic Biol Med. 2023 Apr;199:56-66. Go to original source... Go to PubMed...
    4. Chen J, Li F, Yang W, Jiang S, Li Y. Supplementation with exogenous catalase from Penicillium notatum in the diet ameliorates lipopolysaccharide-induced intestinal oxidative damage through affecting intestinal antioxidant capacity and microbiota in weaned pigs. Microbiol Spectr. 2021 Dec 22;9(3): 18 p. Go to original source... Go to PubMed...
    5. Dutta RK, Lee JN, Maharjan Y, Park C, Choe SK, Ho YS, Kwon HM, Park R. Catalase-deficient mice induce aging faster through lysosomal dysfunction. Cell Commun Signal. 2022 Dec 6;20(1): 22 p. Go to original source... Go to PubMed...
    6. Gebicka L, Krych-Madej J. The role of catalases in the prevention/promotion of oxidative stress. J Inorg Biochem. 2019 Aug;197: 110699. Go to original source... Go to PubMed...
    7. Li Y, Zhao X, Jiang X, Chen L, Hong L, Zhuo Y, Lin Y, Fang Z, Che L, Feng B, Xu S, Li J, Wu D. Effects of dietary supplementation with exogenous catalase on growth performance, oxidative stress, and hepatic apoptosis in weaned piglets challenged with lipopolysaccharide. J Anim Sci. 2020a Mar 1;98(3): 10 p. Go to original source... Go to PubMed...
    8. Li Y, Zhao X, Zhang L, Zhan X, Liu Z, Zhuo Y, Lin Y, Fang Z, Che L, Feng B, Xu S, Li J, Wu D. Effects of a diet supplemented with exogenous catalase from penicillium notatum on intestinal development and microbiota in weaned piglets. Microorganisms. 2020b Mar 11;8(3): 17 p. Go to original source... Go to PubMed...
    9. Nandi A, Yan LJ, Jana CK, Das N. Role of catalase in oxidative stress- and age-associated degenerative diseases. Oxid Med Cell Longev. 2019 Nov 11;2019: 19 p. Go to original source... Go to PubMed...
    10. Perez-Estrada JR, Hernandez-Garcia D, Leyva-Castro F, Ramos-Leon J, Cuevas-Benitez O, Diaz-Munoz M, Castro-Obregon S, Ramirez-Solis R, Garcia C, Covarrubias L. Reduced lifespan of mice lacking catalase correlates with altered lipid metabolism without oxidative damage or premature aging. Free Radic Biol Med. 2019 May 1;135:102-15. Go to original source... Go to PubMed...
    11. Schopping M, Zeidan AA, Franzen CJ. Stress response in Bifidobacteria. Microbiol Mol Biol Rev. 2022 Dec 21;86(4): 59 p. Go to original source... Go to PubMed...
    12. Sepasi Tehrani H, Moosavi-Movahedi AA. Catalase and its mysteries. Prog Biophys Mol Biol. 2018 Dec;140:5-12. Go to original source... Go to PubMed...
    13. Shin SK, Cho HW, Song SE, Song DK. Catalase and nonalcoholic fatty liver disease. Pflugers Arch. 2018 Dec;470(12):1721-37. Go to original source... Go to PubMed...
    14. Skaperda Z, Kyriazis ID, Tekos F, Alvanou MV, Nechalioti PM, Makri S, Argyriadou A, Vouraki S, Kallitsis T, Kourti M, Irene V, Arsenos G, Kouretas D. Determination of redox status in different tissues of lambs and kids and their in-between relationship. Antioxidants. 2022 Oct 20;11(10): 17 p. Go to original source... Go to PubMed...
    15. Sun X, Piao L, Jin H, Nogoy KMC, Zhang J, Sun B, Jin Y, Lee DH, Choi S, Li X. Dietary glucose oxidase and/or catalase supplementation alleviates intestinal oxidative stress induced by diquat in weaned piglets. Anim Sci J. 2021 Jan-Dec;92(1): e13634. Go to original source... Go to PubMed...
    16. Tett A, Pasolli E, Masetti G, Ercolini D, Segata N. Prevotella diversity, niches and interactions with the human host. Nat Rev Microbiol. 2021 Sep;19(9):585-99. Go to original source... Go to PubMed...
    17. Wang J, Liu N, Song M, Qin C, Ma C. Effect of enzymolytic soybean meal on growth performance, nutrient digestibility and immune function of growing broilers. Anim Feed Sci Technol. 2011 Nov 3;169:224-9. Go to original source...
    18. Wang J, Lin L, Li B, Zhang F, Liu N. Dietary Artemisia vulgaris meal improved growth performance, gut microbes, and immunity of growing Rex rabbits. Czech J Anim Sci. 2019 Apr 9;64(4):174-9. Go to original source...
    19. Wang W, Zhu J, Cao Q, Zhang C, Dong Z, Feng D, Ye H, Zuo J. Dietary catalase supplementation alleviates deoxynivalenol-induced oxidative stress and gut microbiota dysbiosis in broiler chickens. Toxins. 2022 Nov 28;14(12): 16 p. Go to original source... Go to PubMed...
    20. Yu M, Zhang C, Yang Y, Mu C, Su Y, Yu K, Zhu W. Long-term effects of early antibiotic intervention on blood parameters, apparent nutrient digestibility, and faecal microbial fermentation profile in pigs with different dietary protein levels. J Anim Sci Biotechnol. 2017 Aug 1;8: 12 p. Go to original source... Go to PubMed...
    21. Zhao H, Zhang F, Chai J, Wang J. Effect of lactic acid bacteria on Listeria monocytogenes infection and innate immunity in rabbits. Czech J Anim Sci. 2020 Jan 9;65(1):23-30. Go to original source...
    22. Zhou T, Cheng B, Gao L, Ren F, Guo G, Wassie T, Wu X. Maternal catalase supplementation regulates fatty acid metabolism and antioxidant ability of lactating sows and their offspring. Front Vet Sci. 2022 Nov 23;9: 13 p. Go to original source... Go to PubMed...

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