Pogány Simonová M. author Lauková A. author Chrastinová Ľ. author Strompfová V. author Faix Š. author Vasilková Z. author Ondruška Ľ. author Jurčík R. author Rafay J. author text journal article 2009 The effect of Enterococcus faecium CCM7420, bacteriocin-producing strain with probiotic properties and its partially purified bacteriocin PPB CCM7420 on growth performance, microflora, Eimeria sp. oocysts, biochemical blood parameters and glutathione-peroxidase activity in rabbits was determined. An increase in the body weight of rabbits (P < 0.01) was achieved after E. faecium CCM7420 application. A non-significant reduction of faecal E. coli (including haemolytic E. coli), coagulase-positive staphylococci (CPS) and Staphylococcus aureus was found in rabbits administered the E. faecium CCM7420 strain and lower (non-significant) counts of S. aureus and Clostridium-like sp. were detected in PPB CCM7420 group, compared to the control. In the caecum, a significant reduction of CPS was noted in both experimental groups (P < 0.001 and P < 0.05 for EG1 and EG2, respectively). Biochemical blood parameters increased in both experimental groups (P < 0.05 and P < 0.001 for EG2 and EG1, respectively). In the CCM7420 group, the lowest activity of glutathione-peroxidase was measured (P < 0.001). After the application of PPB CCM7420 (P < 0.05; day 21), a reduction of Eimeria sp. oocysts was recorded. rabbits; microflora; coccidia; enterocins; blood parameters; probiotic 10.17221/1659-CJAS https://cjas.agriculturejournals.cz/artkey/cjs-200908-0005.php https://cjas.agriculturejournals.cz/artkey/cjs-200908-0005.php continuing 54 8 376 386 2009 12121819 periodical academic journal