PT  - JOURNAL ARTICLE
AU  - Hradecká, E.
AU  - Čítek, J.
AU  - Panicke, L.
AU  - Řehout, V.
AU  - Hanusová, L.
TI  - The relation of GH1, GHR and DGAT1 polymorphisms with estimated breeding values for milk production traits of German Holstein sires
DP  - 2008 Jun 30
TA  - Czech Journal of Animal Science
PG  - 238--246
VI  - 53
IP  - 6
AID - 10.17221/362-CJAS
IS  - 12121819
AB  - : We analysed the relations of estimated breeding values (EBV) of 315 German Holstein sires to their genotypes in growth hormone gene (GH1), growth hormone receptor gene (GHR) and acylCoA-diacylglycerol acyltransferase 1 (DGAT1). The strong relation of DGAT1 K232A to the estimated breeding values for milk production traits has been confirmed, when allele DGAT1<sup>K</sup> was connected with higher milk fat yield, milk fat and milk protein content, while allele DGAT1<sup>A</sup> increased milk yield and milk protein yield. The effect of DGAT1 genotype explained from 4.70% of variability of EBVs for fat yield to 31.90% of variability of EBVs for fat content. The evaluation of GH1 127 Leu/Val and GHR 257 SNP polymorphisms did not reveal an association of their polymorphism with EBVs for milk production traits, except the EBVs of GHR<sup>G</sup>/GHR<sup>G</sup> homozygotes for fat yield, which were significantly lower. The effect of GH1 or GHR genotype explained only a negligible portion of variability of EBVs (R<sup>2</sup> < 1.00% in most cases).